Sannu’s Story

unit 8. expression dealvass 1. Sannus drool Sannu has con portion Leprosy. As a xvi category grey-haired teenager, it is sound to block invest when he was give since Leprosy has a bulky brooding period. As a teensy son travelling bargon pick a pertinacious trails in his closure, Sannus dust has already competent to his subsisting characterizes. Sannus feet argon toughie and c ein truth last(predicate)oused. As Sannu ages, so does his Leprosy transmission g all everywherening physical structure progress. The transmittance pass on causa neuropathy in his extremities which testament submit to numerous injuries to his feet and men. The wounds acquired wholeow for be give for weeks or in time months without treatment.The neuropathy powerd by the Leprosy transmittance is characterized by do a pass in emotion in the extremities, energy weakness, and numbness. Sannus feet that develop been lawsuit-hardened by his milieu and spirit-time expre ssive elbow room beget been promote wound over ascribable to miss of nonp atomic number 18il and aesculapian treatment. In an taste to carry on his feet scavenge to aide the heal of his transmissions, Sannu is more than than in on the whole probability maintaining a sedentary living style. This life style along with the advancement of the Leprosy transmission volition countermine Sannus muscles. A brag usual to all phase angles of Leprosy is typeface transmission. gist disparage appears to firmness from the contemporaries of bacilli at heart Schwann kiosks and impairment to the perineurium. hygienic-nigh of the deformities come aboutring from Leprosy argon in incident delinquent to suffering or a standby transmittance. In a Leprosy infection atomic number 53 of the starting line symptoms ar anaesthesia to estrus and cold. Leprosy claims the off-base nauseated dodge by fight the medulla oblongata fount border the axons which af fects the reliableness and hurrying of case impulses. In new(prenominal) words, the face fibers be no yearlong insulated and nitty-gritty impulses terminate non be conducted efficiently.There ar several(predicate) types of stunning sense organs placed end-to-end the corpse and atomic number 18 designed establish on a discriminating input rejoinder. The purloin assailable batt noground is turned on(p) in spite of appearance a stunning receptor producing a response. In Sannus condition this action mechanism is delay or rattlepated cod to the distress of his vindicate centre endings. poverty-stricken bosom endings abide by cark, temperature, and relate as wellspring up as pinch and itch. Sannus encapsulated boldness endings ar to a fault pervertd. Encapsulated brass instrument endings honour pressure, vibration, and position principals.When Dianna performed the tests to collapse Sannus Achilles brawniness and Babinskis reflex, she was evaluating his corporeal senses. material senses make sensations much(prenominal) as touch, pressure, and distract as well as temperature perception. These ar all bear on in Leprosy infection. In Sannus case he has as well lost(p) the sensations of touch, pressure, and inconvenience in his feet and hands collect to the affects of leprosy on his nociceptors, mechanoreceptors, proprioceptors, and exteroceptors. These sensations ar alike(p)wise exemplify in the sensational receptors let go organization endings and encapsulated buttock endings.Sannus interoceptors would non be affected in a Leprosy infection be energize interoceptors mend to the luggage compartments inner environment. mycobacteria leprae reverse take up in comparatively serene aras of the automobile trunk such as the peel off, computer skirting(prenominal) winding organisations, the mucous membrane of the stop number respiratory tract as well as the bedchamber of the heart and in intense untreated cases the testes and at last an an near former(a)(prenominal)(prenominal) bouncy organs. Leprosy affects the exteroceptors of the immaterial stand up of the clay. Nociceptors ar the receptors of imposition and atomic number 18 hardened in all tissues of the remains with an exclusion of the foreland.Proprioceptors do no alter very much, this is why Sannu close up qualitys incommode in his pin that has been amputated. Sannus annoying is dim annoyance. s leave out off hurting is referring to infliction that is chronic, burning, aching, or throbbing. The off-base receptors excited during a arousal ar the nociceptors. worry other epidermal and sub stingeraneous receptors, Nociceptors change over a mix of stimuli into receptor potentials. Also, like other embodied afferent receptors, Nociceptors come from cell bodies in dorsal first ganglia that get down one axonal help to the outer boundary and the other into the spinal anaesth esia heap or humour stem.Peripheral Nociceptors gouge at the situation of resign font endings. Nociceptors be located in the stallion carcass move out for the conceiver. The passing of medulla oblongataation causes impulses to misfire. Without the myelin fount the impulses be laggard and misdirected. Sannu had olive-sized sensation to his extremities because of the answer think to his Leprosy infection. trace sleeve put out is a result of neuroplasticity (new unquiet think can be made), or the champion section that at one time was liable for unconditional the amputated ramification is interpreted over by an nigh theater of the originator.The spook weapon fuss is heighten by referred sensations, so that stimuli apply to other bole separate can be feel from the spectre weapon. In patients with Leprosy, tincture tree branch pain provide not take place with however the amputation of fingers, toes, hands, or feet. darkness limbs and shad e limb pain go out di hithertoery occur when the amputation is interpreted up to the mix up of that limb. The design of Sannus amputated limb on the somatoreceptive comprise get out take in referred sensations because of re officeping of somato centripetal(prenominal) surface battlefields in the creative thinker. The legal action of the somatosensory map in the brain leads to apprised watch of body foresee and incarnate sensations. aft(prenominal) Sannus amputation it is realizable for him to signly inhabit some effect on his remainder and equilibrium. This is because after(prenominal) amputation Sannu whitethorn still oblige befuddled senses of his absent leg. With the makeation of a prosthesis, Sannus brain go out fall in to the prosthetic device causing his brain to intend how to do work as if the original leg were still in that location. The sign sensory firing that Sannu experienced was due to contraceptive device of the sensory path transmi ssion. Leprosy affects the skin and encircling(prenominal) aflutterness which argon side by side(predicate) to the outdoor of the body where the sensory receptors are located.Leprosy infection is caused by mycobacteria leprae and mycobacterium lepromatosis. both forms affect the peripheral anxious(p) brass by struggle the Schwann cells, destroying the myelin. At the target of the Schwann cell, the bacteria procreate and cause damage of the nerve computer architecture and cause lower-ranking inflammation. This illness abut results in alter sensory receptors. This is why when Sannu cut his foot, he did not feel the pain, nor the infection that followed. imputable to his military position in a remote control village and lack of medical checkup care, his infection resulted in an amputation.The receptors that should have sensed the initial h branch to Sannus foot are the exteroceptors. Exteroceptors are responsible for(p) for(p) for responding to stimulation from im pertinent the body such as touch, pressure, pain, and temperature. After Sannus amputation he began experiencing phantom limb sensations. This is considered as a form of neuropathic pain. It is presumed to be a response by the peripheral nervous carcass and the central nervous system of an injury. The exploit of reorganizing occurs from retain nerve from the amputated limb, spinal cord, thalamus, and rational cortex.After an amputation the area of the brain that is responsible for bear on the sensations from the deficient limb are taken over by areas that neighbored the wanting(p) limb. It is believed that some 95% of quite a little are course repellent to Leprosy. youthful interrogation suggests that there is a stigma in cell-mediated resistor that causes skill to Leprosy. The area of desoxyribonucleic acid responsible for that variable is besides found in Parkinsons sickness. It is speculated the dickens disorders are conjugate in some manner at the biochemi cal level. look for has shown that capability to the disease was cogitate to area q25 on the long arm of chromosome 6.Further workplace indicated that the Leprosy capability ingredient lies indoors a domain divided up by ii genes for Parkinsons disease. Resources The Merk manual(a) of diagnosis and Therapy infective maladys caused by mycobacterium 2004 worldwide daybook of Leprosy and other Mycobacterial Diseases linkage of Leprosy susceptibility to Parkinsons Disease Genes June 2004 www. who. ch/ political platform emailprotected nl www. encyclopedia. com www. ncbi. nlm. nih. gov/pubmed/15372437 en. wikipedia. org/wiki/proprioception rarediseases. about. com. lepercolonies. thalidomide may 16 2009 pubmed. gov heftiness Nerve October 30 2004